‘Movement Disorders’ Articles

Clinical Skill is Paramount in Choosing the Best Ataxia Test

When a patient presents with ataxia, a diagnostician must synthesize an extraordinary amount of clinical information to guide his or her differential diagnosis. Genetic testing is guided by this process and is based on the findings of a thorough neurological exam, family history, and other Read more

  • October 26, 2015
  • 01:38pm EDT

SCA13: Helping One Family

A major challenge in modern genetic testing is determining whether a new variant is benign or pathogenic. For Michael Waters, MD, PhD, of the McKnight Brain Institute at the University of Florida in Gainesville, that challenge led him to a new discovery about a gene Read more

  • May 02, 2013
  • 04:56pm EDT

Study Leads to Deeper Understanding of Genetics of Early-Onset PD

New findings from an ongoing genetic study of early-onset Parkinson’s disease indicate that relatives of individuals carrying parkin mutations are at increased risk for PD themselves. In addition, juvenile-onset PD can be due to any one of several known PD genes, and likely other genes Read more

  • April 29, 2013
  • 04:23pm EDT